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To get the maximum benefit from your medication, it is advisable not to drink excessive amounts of alcohol before taking this medication. A double-blind, placebo-controlled exercise stress trial evaluated 144 patients with erectile dysfunction and chronic stable angina who regularly received anti-anginal medicinal products (except nitrates). The results demonstrated no clinically relevant differences between sildenafil and placebo in time to limiting angina. Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum, where PDE5 is responsible for degradation of cGMP. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum but potently enhances the relaxant effect of NO on this tissue. When the NO/cGMP pathway is activated, as occurs with sexual stimulation, inhibition of PDE5 by sildenafil results in increased corpus cavernosum levels of cGMP.

You should not use SildenafilI with treatments for pulmonary arterialhypertension (PAH) containing sildenafil or any other PDE5 inhibitors. Currently the only dose of Viagra available over the counter in the UK is 50mg, which is available as Viagra Connect. Other doses may become available over the counter in the future.You can buy all doses of Viagra online without having to see a doctor or pharmacist face-to-face.

This is the standard starting dose of Viagra, and is usually what a doctor will recommend if you’ve never tried Viagra before. Viagra 50mg is effective and safe for most men to take, and is the most commonly-used dosage. This is also the only dose you can buy over the counter in the UK. The dosage refers to how much of the active ingredient (sildenafil citrate) is in the tablet.

Learn about the causes, treatment and how to prevent complications. Find out what questions a doctor may ask when discussing erectile dysfunction&nbsp